I think it depends on your preference and also on how experienced you are with cryptocurrencies. Meme coins are not like Bitcoin, which has two seasons, such as the bull and bear seasons. During bull season, so many altcoins usually get pumped, but not all. If you are unlucky to invest in a meme coin that can pump during the Bitcoin bull market, then you will experience a loss on your investment. Apart from that, some meme coins usually generate huge profits for some investors, but the disadvantage is that no one can be very sure about the right coin to invest in.
While investing in meme coins, it's wise to invest only the amount that you can afford to lose.