Plenty of time till the next round, scheduled for 21st/22nd January, but we only have two rounds to go in the first-ever league stage.
I don't expect there to be any major changes in the top 8 (which will progress to the next round without play-offs). Some ay Brest, currently ranked 7th, doesn't belong there and expect them to drop down, but I think they can handle Shakhtar Donetsk in the next round, and even if they lose to Real in the final round, they should still have enough points to go through.
Similar thing with Aston Villa. Their Premier League performance was far from impressive recently, but the remaining UCL games are not the hardest ones (Monaco away and Celtic at home) so they'll probably earn at least 3-4 points which should be enough to stay in the top 8.
LOSC Lille might struggle to hold on to their current 8th place, as they're playing their next game against Liverpool, who are unstoppable lately, but, as the British team is already guaranteed to go through to the next round, they might go easier on the French.