Someone who has been in the bitcoin space for a long time should set a target and they will not miss the opportunity to take advantage when their target is reached. Unless they are beginners who are still enthusiastic, even though without realizing they are following greed.
Both experienced and new holders must have a target. But experienced holders will set a reasonable target, they won't set a too high target. I think $100k is very reasonable target, many people predict the price of Bitcoin will reach $100k. It is different with new holders, they may set too high target because they are too greedy. They think Bitcoin so easy to skyrocket, they don't know it must be based on some factors.
There are also people who set 2 targets, for example until bitcoin reaches 100k and reaches 150k. When it reaches 100k they will sell some and hold the other part until their second target is reached.
Yes, most people target to take profits at $100k and $150k. I think there is no problem to set a target at $150k. But it looks like a more difficult to achieve, I personally don't brave because I don't want to take a too high risk. I prefer to set a target at $100k, I think it is a bit safe as a target for taking profits.