I'm very sure, each holder must have a specific price for selling their coins. It is just very strange if someone has no certain price for selling the coins. However, it is better to make a reasonable price for the target of selling the coins. There are some people who target too high prices for certain coins. It will make a big chance of missing the best time for selling the coins. Even it is for Bitcoin, it must be with a reasonable price for selling it.
Indeed, holders must set certain prices for selling their coins. We don't hold without clear target for profits. This can end up with missing many chances for profits. The holders must have certain ways to determine their selling targets. It must be based on a research and analysis. But to set the target for selling Bitcoin is easier than altcoins. For altcoins, it is very difficult to predict, they are very volatile and can be very surprising.
Economically speaking, setting a profit target for a trader/investors does not require much experience. For example, a trader who bought one Bitcoin at $78k do not require any calculations or search through the past trends to know his selling target.
A trader is expected, to at least, close his position once the price touches $81k, for instance. As trader or holder, he is expected to Take profits and not wait until price goes to the moon, as people will always assume the price will go.
You see, the market is unpredictable, at little profit margin, may worth taking some profits, except for an investor that planned to hold for many years, he may ignore the short time increase, hoping for the future price increase.