The best way to invest is to diversify risks, so I think that a good option would be for example invest 40% in Bitcoin, 30% in Ethereum, Zcash, DASH, NEO, EOS, 20% in promising, but riskier coins: 0x, HBZ, ZRX, IPSX, FJC, ECC, BQ and the remaining 10% to invest in ICO. Of course, you can invest using a more risky scheme, but it is better to reduce the risks and get financial profit.